Document Type
Article
Abstract
Irradiation with ~ 3 MeV proton fluences of 10⁶ - 10⁹ protons cm⁻² have been applied to study the effects on human brain tissue corresponding to single-cell irradiation doses and doses received by electronic components in low-Earth orbit. The low fluence irradiations were carried out using a proton microbeam with the post-focus expansion of the beam; a method developed by the group of Breese [1]. It was found from electrophysiological measurements that the mean neuronal frequency of human brain tissue decreased to zero as the dose increased to 0 to 1050 Gy. Enhancement-mode MOSFET transistors exhibited a 10% reduction in threshold voltage for 2.7 MeV proton doses of 10Gy while a NPN bipolar transistor required ~800 Gy to reduce the h��ₑ by 10% which is consistent the expected values.
Publication Date
2019
Recommended Citation
Whitlow, Harry J.; Guibert, Edouard; Jeanneret, Patrick; Homsy, Alexandra; Roth, Joy; Krause, Sven; Roux, Adrien; Eggermann, Emmanuel; and Stoppini, Luc, "Post-focus expansion of ion beams for low fluence and large area MeV ion irradiation: Scaling from the single-event to the system level in human brain tissue and electronics devices" (2019). Louisiana Accelerator Center. 10.
https://scholarshub.louisiana.edu/lac/10
Comments
Received 30 December 2016, Accepted 23 January 2017, Available online 22 February 2017